According to media, as of 6 January 2026, 76 suspected and six confirmed mpox cases have been reported across six regions: Boeny, Analamanga, Atsimo-Andrefana, Diana, Vakinankaratra, and Itasy. Reports do not indicate which clade has been detected.
This is the first mpox outbreak in Madagascar which was not listed among affected countries during the 2022–2023 global mpox outbreak, nor during the ongoing clade I activity reported in parts of Africa between 2023 and 2025.
Risk very low for general populations but moderate for at risk groups.
- Avoid close, skin-to-skin contact with individuals who have, or may have, mpox, including anyone with a rash (pimples, blisters, scabs).
- Wash hands frequently with soap and water or use an alcohol-based hand sanitiser at least 60% alcohol).
- Avoid touching potentially contaminated personal items such as bedding, clothing, towels, cups, or eating utensils used by someone with suspected or confirmed mpox.
- Avoid sexual contact with sick persons; use condoms for up to 12 weeks if your sexual partner has had mpox.
- Follow recommendations issued by local health authorities.
- For people belonging to an at-risk group, vaccination may be indicated. See Mpox factsheet.
- Avoid contact with animals in areas where mpox regularly occurs. Avoid eating or preparing meat from wild animals (bushmeat) or using products (creams, lotions, powders) derived from wild animals.