Ethiopia has faced malaria outbreaks in numerous regions since early 2023. The regions most affected include Gambela, Southwest Ethiopia (SWEPR), Afar, and Ahmara. 

In addition to malaria, Ethiopia faces other health crises, including cholera, measles, dengue fever, and COVID-19, as well as a variety of natural disasters such as droughts, recurrent floods, food insecurity, and locust infestations, as well as man-made challenges such as conflict, internal displacement, and the effects of the Sudan conflict. These factors combined have significantly increased the country's need for health and humanitarian assistance.